The Native® implant is composed of a porcine derived dermal matrix with a 0.6 mm thickness. The exclusive production process which Native® undergoes was developed in order to guarantee a completely natural product, non cross-linked, and without the presence of any chemicals which can amplify the inflammatory phenomenon and slow down the regular progression of tissue regeneration.



The native protein structure gives Native® immediate bioavailability.

To guarantee the characteristics of Native® over time, the final phase of the production process includes freeze-drying to remove all liquids using exact pressure and temperature values.

This process makes the final product dry, excellent for correct storage at room temperature and which only requires simple rehydration before the implantation. The Native® membrane can be cut at the surgical site.


Native® Development

Native® ADM which is 0.6 mm thick is free from processing residue and preservatives to provide immediate bioavailability. Native® is completely transformed into self-tissue mitigating inflammatory phase complication.

Quality controls make the difference between random and predictable performance. Strict compliance with European standards (CE Mark and ISO Standards) for the production process are the guidelines for processing a safe biomaterial, but in our company, quality control is the strictest phase because we know just what a patient’s expectations mean to a surgeon.

One-step breast reconstruction, when indicated, has revealed important benefits both for the patient who recovers her physical integrity with just one operation, and for its significant cost savings. The advent of biomaterials has greatly contributed to this method by substantially improving aesthetic results.

Innovation of Native®

The biomaterials available for breast reconstruction are generally the same ones used in hernia repair.

Polypropylene, engineered silk, ADM including cross-linked, possess the mechanical resistance aimed at supporting endo-abdominal pressure and when it happens, they are reabsorbed slowly to prolong over time the shield effect on the muscle fascia. Instead, breast reconstruction requires a biomaterial that stimulates the incorporation process as quickly as possible in order to reduce the risk of early complications such as prolonged collection of seroma.

The extracellular matrix structure is essential for the regenerative process since it acts as a target site for the integrins. These glycoproteins are present on the cell membrane. One of their most important functions is the role they play in cell migration towards compatible environments. They determine the cell decision on which biological action to undertake and mediate the relationships between the extracellular matrix and the cell itself.

The main functions of the extracellular matrix are:

  • Acceleration of cell migration.
  • Maintenance of differentiated phenotype.
  • Scaffold for regeneration.
  • Accumulation and presentation of growth factors to target cells.

The Native® porcine dermal matrix has been designed to reduce negative inflammatory phenomena to a minimum such as body temperature changes, skin flare or prolonged seroma collection.


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